Three hard screens, in order. Floor plate depth — past roughly 90 feet window-to-window and you get dark interiors no layout fixes. Plumbing — office cores cluster wet stacks centrally; residential wants them distributed, and re-running risers is where budgets die. Curtain wall — if it can't open or be cheaply modified, your operable-window requirement just bought a new facade.
A building has to pass all three before the incentive math is even worth running. Most towers fail at floor plate.